The majority of fallopian tube cancers are papillary serous adenocarcinomas, which grow from the cells that line the inside of the fallopian tubes. They make up about one percent of all gynecological cancers, and their major known risk factor is genetic mutation, primarily in the BRCA1 gene, which also causes breast and ovarian cancer in women, and prostate cancer in men. Treatment will vary depending on the stage and grade of the cancer, but can involve a radical hysterectomy, wherein the uterus, ovaries, and fallopian tubes are all surgically removed.
Chemotherapy is usually administered before surgery to shrink the tumour, or after a recurrence to kill remaining cancer cells. Occasionally, tamoxifen, a hormonal therapy, might be used to treat tumours that are responsive to hormones.